What is the brand name for camptothecin?
Camptosar is the trade name for irinotecan. Camptothecin-11 and CPT-11 are other names for irinotecan. In some cases, health care professionals may use the trade name camptosar or other names camptothecin-11 or CPT-11 when referring to the generic drug name irinotecan.
What are other names for camptothecin?
Topoisomerase I Inhibitors (Camptothecins—Irinotecan, Topotecan) Camptothecin is a naturally occurring alkaloid derived from the plant Camptotheca acuminata that was identified in an anticancer drug discovery screen in the 1960s.
Is topotecan a camptothecin?
Warren Ross developed topotecan (NSC 609699),1 a semisynthetic, water-soluble analog of camptothecin.
What class of drug is topotecan?
Topotecan is in a class of medications called topoisomerase I inhibitors. It works by killing cancer cells.Oct 15, 2016
What is the generic name for camptothecin?
Generic and brand names of antineoplastics CPTs include: Camptosar. Hycamtin. Irinotecan.
What are other names for irinotecan?
Irinotecan is a type of chemotherapy. It is also known by its brand name Campto. It is a treatment for cancer that started in the bowel (bowel cancer). This includes the colon and back passage (rectum).
What is the generic name of irinotecan?
Camptothecin-11 and CPT-11 are other names for irinotecan. In some cases, health care professionals may use the trade name camptosar or other names camptothecin-11 or CPT-11 when referring to the generic drug name irinotecan.
What is the drug name for camptothecin?
Drug type: Irinotecan is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as a "plant alkaloid" and "topoisomerase I inhibitor." (For more detail, see "How this drug works" section below).
What drugs are camptothecin analogues?
Four CPT analogues have been approved and are used in cancer chemotherapy today, topotecan, irinotecan, belotecan, and trastuzumab deruxtecan. Camptothecin has also been found in other plants including Chonemorpha fragrans.
Which of the following camptothecin analogs is used to treat ovarian cancer?
Topotecan and irinotecan
Camptothecins produce their cytotoxic effects via inhibition of topoisomerase I, which causes single-strand breaks in DNA. Topotecan is indicated for the treatment of metastatic ovarian carcinoma, relapsed and refractory cervical cancer, and as second-line therapy for small cell lung cancer.